Christine LE-ROY
Research Officer
Christine has always been driven by the study of cellular signaling and the mechanisms of disease progression. She holds a PhD in Metabolism, Endocrinology, and Nutrition from the University of Lyon 1, where she researched the autocrine and paracrine regulation of steroidogenic cells. Following her doctoral studies, she completed an extensive postdoctoral fellowship at the Samuel Lunenfeld Research Institute in Toronto, focusing on TGFβ receptor signaling and trafficking. In 2007, she shifted her focus to hematology at the Institut Cochin, investigating alterations in BCR signaling in patients with Chronic Lymphocytic Leukemia (CLL). In 2009, Christine was recruited as a Research Scientist (CR1) at INSERM within the UMR 1349 unit in Bobigny. She obtained her Habilitation à Diriger des Recherches (HDR) in 2013, focusing on the structural and functional analysis of the Syk interactome in normal and pathological hematopoiesis. Throughout her career, she has developed deep expertise in B-cell malignancies, focusing on cellular plasticity and signaling heterogeneity to develop translational models to predict disease progression.
Since 2021, Christine has served as the Deputy Director of UMR 1349 (SIMHEL) under the direction of Dr. N. Varin-Blank. Her leadership extends to her role as Deputy Director of the SFR “Pathophysiological, Epidemiological, Participative and Societal approaches to chronic diseases” created in 2025 by USPN and her long-standing coordination of translational collaborations between research teams and hospital clinicians. An active member of the academic community, she is an elected member of the University Research Committee and serves as the Head of the Multi-Array technical platform.