Elisabetta Dondi
Research Engineer
E.Dondi earned a PhD in Genetics from the University of Pavia focusing on molecular and functional analysis of MHC class II genes in humans and mice. She then joined, as a postdoctoral researcher, the Pasteur Institute (Unitè de Signalisation des Cytokines, Dr. S. Pellegrini) where she characterized the modulation of the response to human IFN-a/b and its role in T cell differentiation. She moved to the Cochin Institute (U567, Dr. N. Varin-Blank) for a second post-doctoral fellowship, investigating the role of adaptor proteins APS/Lnk and Vav in. B cell development.
In 2012, she was recruited as a Research Engineer at Université Sorbonne Paris Nord at the U978 now U1349.
Her current research projects are centered on the interactions between tumor cells and microenvironment cells in chronic lymphocytic leukemia (CLL) which support immune surveillance escape leading to disease progression and resistance to current therapies. Particularly, she is focusing on 1) elucidating the molecular mechanisms underlying the bidirectional crosstalk between CLL B cells and M2-macrophages, referred as nurse-like cells (NLCs); 2) analyzing the spatial interactions between the cellular and molecular components of the tumor microenvironment on lymph node biopsies.
Since 2010, she is scientific and administrative co-responsible of the TisCel13 cytometry platform at the UFR-SMBH, Université Sorbonne. Paris Nord.